Flavin-Containing Monooxygenase-5, Microsomes human,1VIAL,F5178-1VL,Sigma

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订货号 : 0BL1773
品牌型号 : Sigma F5178-1VL
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

Application

FMO5 is the only FMO isoform expressed in both adult and fetal human liver.


Biochem/physiol Actions

FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.


Physical form

Solution in 100 mM potassium phosphate buffer, pH 7.4.


Other Notes

methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide.


技术参数 Specifications
recombinantexpressed in baculovirus infected insect cells
Quality Level200
formbuffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
specific activity≥700 units/mg protein
mol wt 55-60 kDa
packagingvial of 2.5 mg
UniProt accession no.P49326
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... FMO5(2330)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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