CD40L, Soluble human,10UG,SRP8044-10UG,Sigma

销售价: ¥ 5702.01 / 件
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订货号 0BL0815
品牌型号 Sigma SRP8044-10UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

CD40L (cluster of differentiation 40 ligand) belongs to the tumor necrosis factor (TNF) family, and is expressed by basophils, B cells, monocytic cells, natural killer cells, platelets, mast cells and T cells. It is predominantly expressed on pro-inflammatory T cells. It also exists in a soluble form.


Biochem/physiol Actions

CD40L (cluster of differentiation 40 ligand) is active in its membrane-bound form. It interacts with CD40 and functions as a proinflammatory and procoagulant agent. The serum levels of soluble CD40L is elevated in malignant middle cerebral artery infarction (MMCAI) patients, especially in non-surviving patients.


Physical form

Lyophilized from PBS


Preparation Note

Reconstitute with 100 μL deionized water.


Other Notes

Human CD40L (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.


Legal Information

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany


技术参数 Specifications
biological sourcehuman
recombinantexpressed in CHO cells
tagFLAG® tagged
assay>95% (SDS-PAGE)
formlyophilized
mol wt 35-40 kDa by SDS-PAGE
packagingpkg of 10 μg
storage conditionavoid repeated freeze/thaw cycles
impurities<0.01 EU/μg endotoxin, tested
UniProt accession no.P29965
shipped inwet ice
storage temp.−20°C
Gene Informationhuman ... CD40LG(959)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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