规格
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Amino Acid Sequence:
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Fluorescein-GAGRLGRDKYKTLRQIRQ |
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Assay Entry:
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Biochemical terbium phospho-specific activity |
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Detection Method:
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Fluorescent |
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Gene ID (Entrez):
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120892 |
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Label or Dye:
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FITC (Fluorescein) |
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Shipping Condition:
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Dry Ice |
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Substrate:
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ERM (LRRKtide) |
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Substrate Properties:
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Peptide-Based Substrate |
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Target Entry:
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LRRK2 D1994A, LRRK2 R1441C, LRRK2 I2020T, LRRK2 G2019S, LRRK2 |
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Target Enzyme:
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Serine⁄Threonine Kinases |
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Validated Kinases:
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LRRK2 |
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Substrate Type:
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Kinase Substrate |
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Molecular Weight:
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2475.8 Da |
储存
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400 µM Fluorescein-ERM (LRRKtide) peptide substrate in water. Store at -20°C and protect from light. |
A fluorescein-labeled peptide substrate based upon ezrin/radixin/moesin (ERM) that is phosphorylated by LRRK2 and LRRK2 mutants.
For use in combination with the LanthaScreen® Tb-anti-ERM (pLRRKtide) Antibody (PV4899) to evalute inhibitors in medium to high throughput screening applications.