规格
|
Accession Number:
|
NP_004194 |
Protein Form:
|
Full Length, Recombinant |
Shipping Condition:
|
Dry Ice |
Molecular Weight:
|
80.8 kDa |
Validated Application:
|
Kinase Assay |
Expression System:
|
Insect |
KinaseFamily:
|
WEE Kinase Family |
Protein Length:
|
Full Length |
Protein Tag:
|
GST Tag |
储存
|
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 50 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol |
This PKMYT1 recombinant human protein (full length) was expressed in insect cells. PKMYT1 serine/threonine kinase is a member of a family of neural specific, zinc finger-containing DNA-binding proteins which binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. MYT1 of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. The recombinant PKMYT1 fragments containing either the upstream 2 zinc fingers or the downstream 4 zinc fingers bound the same cis regulatory element in the PLP1 promoter in vitro and DNA binding required Zn2+, but not other divalent cations. PKMYT1 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service