IFN-α Antibody, anti-human, PE，130-123-947，美天旎

Type I interferons (IFNs), including IFN-α, are a family of cytokines that exert pleiotropic functions in the immune system. Besides its potent antiviral activity, IFN-α exerts a variety of immunomodulatory effects, including positive and negative regulation of its own production, regulation of IL-12 and IFN-γ production, promotion of natural killer (NK) cell cytotoxicity, activation and maturation of dendritic cells, and the promotion of B cell development towards plasma cells. IFN-α is expressed predominantly by CD123⁺CD11c^-CD303 (BDCA2)⁺ plasmacytoid dendritic cells (pDCs). Clone LT27:295 recognizes the majority of the IFN-α subtypes, including IFN-α2b.

IFNA1

Technical specifications