PDK4 (PDHK4) 1 MG，PV5711，Invitrogen

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订货号： 1NE3380

品牌型号： Invitrogen PV5711

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最小订货量： 1套

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商品介绍
规格参数
包装参数

产品介绍 Product Description

规格
Accession Number:	NP_002603.1
Kinase Group:	Ser⁄Thr Kinases: Atypical
Shipping Condition:	Dry Ice
Expression System:	Baculovirus
Form:	Frozen
Protein Form:	Full Length
Research Category:	Drug Development
Species:	Human
Validated Application:	Kinase Assay
Molecular Weight:	73.9 kDa
Gene Alias:	PDK-4 (PDKH4)
KinaseFamily:	PDHK Kinase Family
Protein Tag:	GST Tag

储存
50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Trition X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol. Kinase proteins are shipped on dry ice. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

PDK4 (PDHK4), along with the other PDHKs, regulates glucose metabolism by phosphorylating the E1 alpha subunit of the mitochondrial pyruvate dehydrogenase complex. Inhhibition of PDHKs is viewed as a potential therapeutic treament for type II diabetes.