CD140a-APC, mouse, REA637, 100 tests,130-122-942,美天旎

销售价: ¥ 1475.78 / 件
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订货号 1GR2778
品牌型号 美天旎 130-122-942
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Clone REA637 recognizes the mouse CD140a antigen, a single-pass type I membrane protein, also known as platelet-derived growth factor receptor alpha (PDGFRα). CD140a is a receptor tyrosine kinase that forms homodimers or heterodimers with CD140b (PDGFRβ). Receptor dimerization and transphosphorylation at tyrosine residues activates the intracellular kinase activity. CD140a is broadly expressed in embryonic tissue, mostly in cells of mesodermal origin in adult tissue, and embryonic stem cell–derived cardiomyogenic cells. Expression of CD140a is associated with various malignancies.

Additional information: Clone REA637 displays negligible binding to Fc receptors.


Alternative names

PDGF-R-alpha, PDGFR-alpha, PDGFR-α


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