N-C16-desoxymethylsphinganine,1MG,1246298-42-9,860463P-1MG,Avanti

销售价: ¥ 4055.03 / 件
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订货号 : 0BX8796
品牌型号 : Avanti 860463P-1MG
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

N-C16-desoxymethylsphinganine is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of N-acylsphinganines (dihydroceramides) levels and accumulation of sphinganine. Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.


Biochem/physiol Actions

Dihydroceramides are also used for dihydrosphingolipids synthesis. Treatment of MCF7 cancer cells with fenretinide alters sphingolipid metabolism.


Packaging

5 mL Amber Glass Screw Cap Vial (860463P-1mg)
5 mL Amber Glass Screw Cap Vial (860463P-5mg)


Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


技术参数 Specifications
assay>99% (TLC)
formpowder
packagingpkg of 1 × 1 mg (860463P-1mg),pkg of 1 × 5 mg (860463P-5mg)
manufacturer/tradenameAvanti Research™ - A Croda Brand 860463P
lipid typesphingolipids
bioactive lipids
shipped indry ice
storage temp.−20°C
SMILES string[H][C@](CCCCCCCCCCCCCCC)(O)CNC(CCCCCCCCCCCCCCC)=O
InChI1S/C33H67NO2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-32(35)31-34-33(36)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h32,35H,3-31H2,1-2H3,(H,34,36)/t32-/m1/s1
InChI keySCCABQBVDWFVHP-JGCGQSQUSA-N
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