- 商品介绍
- 规格参数
- 包装参数
General description
N-C16-desoxymethylsphinganine is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of N-acylsphinganines (dihydroceramides) levels and accumulation of sphinganine. Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.
Biochem/physiol Actions
Dihydroceramides are also used for dihydrosphingolipids synthesis. Treatment of MCF7 cancer cells with fenretinide alters sphingolipid metabolism.
Packaging
5 mL Amber Glass Screw Cap Vial (860463P-1mg)
5 mL Amber Glass Screw Cap Vial (860463P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
| assay | >99% (TLC) |
| form | powder |
| packaging | pkg of 1 × 1 mg (860463P-1mg),pkg of 1 × 5 mg (860463P-5mg) |
| manufacturer/tradename | Avanti Research™ - A Croda Brand 860463P |
| lipid type | sphingolipids bioactive lipids |
| shipped in | dry ice |
| storage temp. | −20°C |
| SMILES string | [H][C@](CCCCCCCCCCCCCCC)(O)CNC(CCCCCCCCCCCCCCC)=O |
| InChI | 1S/C33H67NO2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-32(35)31-34-33(36)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h32,35H,3-31H2,1-2H3,(H,34,36)/t32-/m1/s1 |
| InChI key | SCCABQBVDWFVHP-JGCGQSQUSA-N |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |




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