- 商品介绍
- 规格参数
- 包装参数
General description
Pinch-1 (Particularly interesting new Cys-His protein 1) is also known as LIM and senescent cell antigen-like-containing domain protein 1 (LIMS1). Pinch-1 is expressed in most tissues except for brain. Pinch-1 is an adhesion protein and is part of the ILK-PINCH complex that is involved in integrin and growth factor signaling by coupling surface receptors to downstream signaling molecules related to the regulation of cell survival, cell proliferation and cell differentiation.
~40 kDa observed. Uniprot describes 4 isoforms produced by alternative splicing at ~38 kDa, ~44 kDa, ~37 kDa, and ~42 kDa
Immunogen
KLH-conjugated linear peptide corresponding to human Pinch-1.
Application
Anti-Pinch-1 Antibody, clone 9D2.1 is a highly specific mouse monoclonal antibody, that targets Pinch-1 & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Pinch-1 in human renal tubules and mouse renal tubules tissue.
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)
Physical form
Format: Purified
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Human heart tissue lysate
Evaluated by Western Blotting in human heart tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Pinch-1 in 10 µg of human heart tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 9D2.1, monoclonal |
| species reactivity | human, mouse |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| isotype | IgMκ |
| NCBI accession no. | NP_001180411 |
| UniProt accession no. | P48059 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... LIMS1(3987) |
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