Anti-IL-33 Antibody,100UG,ABF108,Sigma

销售价: ¥ 2904.51 / 件
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订货号 : 0BW0036
品牌型号 : Sigma ABF108
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor, leading to the activation of MAP kinases and NF-kappaB. IL-33 induces production of helper T-cell type 2 (TH2) cytokines, including IL-4, IL-5 and IL-13, and is a known mediator of many inflammation responses. Cat. No. ABF108, Anti-IL-33, is an affinity purified rabbit polyclonal antibody that recognizes epitopes in the C-terminal half of murine IL-33. Reactivity to rat or other species has not been tested.
~35 kDa observed. Uncharacterized band(s) may appear in some lysates.


Immunogen

Epitope: C-Terminal
His-tagged recombinant protein corresponding to the C-Terminal of mouse IL-33.


Application

Anti-IL-33 Antibody is an antibody against IL-33 for use in Western Blotting, Flow Cytometry.
Flow Cytometry Analysis: 0.25 µg of this antibody from a representative lot detected IL-33 in 1X10E6 monensin treated MEF1 cells.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology


Physical form

Affinity
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.


Preparation Note

Stable for 1 year at 2-8°C from date of receipt.


Analysis Note

Evaluated by Western Blotting in MEF1 cell lysate.

Western Blotting Analysis: 0.1 µg/mL of this antibody detected IL-33 in 10 µg of MEF1 cell lysate.


Other Notes

Concentration: Please refer to lot specific datasheet.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
purified byaffinity chromatography
species reactivitymouse
technique(s)flow cytometry: suitable,western blot: suitable
NCBI accession no.NP_598536
UniProt accession no.Q8BVZ5
shipped inwet ice
target post-translational modificationunmodified
Gene Informationmouse ... Il33(77125)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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