- 商品介绍
- 规格参数
- 包装参数
General description
Rac1 is a member of a RhoGTPase subfamily (Rac1-Rac4) that transduces extracellular signals from G-coupled protein receptors (GPCR), integrins and growth factor receptors to effector molecules that modulate multiple signaling pathways. While Rac1 supports the activation of MAPkinase pathways and gene activation, it’s most important functions include the regulation of cytoskeletal structures. Together with Rho (regulator of stress fibers) and Cdc42 (regulator of filopodia), Rac modulates the formation of focal adhesion (FA) complexes; membrane ruffles and lamellipodia that contribute to important cell functions related to cell attachment and movement.
21 kDa
Application
Anti-Rac1 Antibody, clone 23A8, Magnetic bead Conjugate detects level of Rac1 & has been published & validated for use in WB & IP.
Biochem/physiol Actions
Other species have not been tested.
Recognizes human Rac1.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt. DO NOT FREEZE! Wash the magnetic beads with an appropriate buffer prior to use to remove sodium azide.
Other Notes
2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | magnetic beads conjugate |
| antibody form | purified antibody |
| antibody product type | primary antibodies |
| clone | 23A8, monoclonal |
| species reactivity | human, rat, mouse |
| technique(s) | immunoprecipitation (IP): suitable,western blot: suitable |
| isotype | IgG2b |
| NCBI accession no. | NP_008839 |
| UniProt accession no. | P63000 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... RAC1(5879) |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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