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- 规格参数
- 包装参数
General description
Calcium-transporting ATPase type 2C member 1 (ATP2C1) is a member of the cation transport ATPase (P-type) (TC 3.A.3) family. ATP2C1 catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. It may also play an important role as a key regulator of insulin-like growth factor receptor (IGF1R) processing in tumor progression in basal breast cancers. It is found in most tissues except colon, thymus, spleen and leukocytes.
~180 kDa observed. Uniprot describes 6 isoforms ranging between ~97 kDa and ~105 kDa Uncharacterized bands may appear in some lysate(s).
Immunogen
KLH-conjugated linear peptide corresponding to human ATP2C1.
Application
Anti-ATP2C1 Antibody is a highly specific rabbit polyclonal antibody, that targets Calcium-transporting ATPase type 2C member 1 & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected ATP2C1 in mouse brain tissue.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Biochem/physiol Actions
This antibody can recognize the three longest isoforms at ~101 kDa, ~103 kDa, and ~105 kDa.
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Mouse brain tissue lysate
Evaluated by Western Blotting/Peptide Inhibition Assay in mouse brain tissue lysate.
Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected ATP2C1 in 15 µg of mouse brain tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | mouse |
| species reactivity (predicted by homology) | human (immunogen homology) |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| UniProt accession no. | P98194 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... ATP2C1(27032) |
| 长度(mm) | |
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