Leukotriene B₄,50UG,434625-50UGCN,Sigma

销售价: ¥ 5291.95 / 件
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订货号 0BV6545
品牌型号 Sigma 434625-50UGCN
货期 询货期
最小订货量 1件
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  • 商品介绍
  • 规格参数
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产品介绍 Product Description

General description

Potent inflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema.
Potent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema and asthma.


Biochem/physiol Actions

Cell permeable: no
Primary Target
Polymorphonuclear leukocytes
Product does not compete with ATP.
Reversible: no


Physical form

In Ethanol.


Preparation Note

Following initial thaw, aliquot and freeze (-70°C).


Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Kendall, A.P., et al. 1995. Anesthesia 50, 590.
Dokter, W.H., et al. 1994. Leukemia 8, 1181.
Jedlitschky, G., et al. 1991. J. Biol. Chem.266, 24763.


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Flammable (J)


技术参数 Specifications
descriptionMerck USA index - 14, 5455
Quality Level100
assay≥97% (HPLC)
formoil
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze
colorclear
solubilityethanol: soluble
shipped inwet ice
storage temp.−70°C
SMILES stringOC(CCCC(=O)O)\C=C\C=C\C=C\C(O)C\C=C\CCCCC
InChI1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6+,14-10+,15-11+
InChI keyVNYSSYRCGWBHLG-XUOUMLBJSA-N
长度(mm)
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