- 商品介绍
- 规格参数
- 包装参数
General description
Signal transducer and activator of transcription 6 (STAT6) transduces signals from extracellular cytokines during adaptive immunity and has recently been found to be important in the innate immune response to viral infection. STAT6 is also involved in the attenuation of the Th1 and Th17 in the nephritogenic immune response. The consequence of STAT6 activity has been associated with the pathogenesis of autoimmune disease and has been found to be actively imported to the nucleus.
~165 kDa observed
Immunogen
Epitope: Phosphorylated (Tyr641)
KLH-conjugated linear peptide corresponding to human STAT6 phosphorylated at (Tyr641).
Application
Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1 is a mouse monoclonal antibody for detection of phospho STAT6 (Tyr641) also known as Signal transducer & activator of transcription 6, IL-4 Stat & has been validated in WB, FC.
Flow Cytometry Analysis: 2 µg/mL from a representative lot detected STAT6 in human peripheral blood leukocytes.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Biochem/physiol Actions
This antibody recognizes STAT6 phosphorylated at (Tyr641).
Physical form
Format: Purified
Protein G Purified
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
NIH/3T3 cell lysates treated and untreated with PDGF
Evaluated by Western Blot in NIH/3T3 cell lysates treated and untreated with PDGF.
Western Blot Analysis: 0.5 µg/mL of this antibody detected STAT6 on 10 µg of PDGF untreated and treated NIH/3T3 cell lysates.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 19E2.1, monoclonal |
| species reactivity | human, mouse |
| technique(s) | flow cytometry: suitable,western blot: suitable |
| isotype | IgG2aκ |
| NCBI accession no. | NP_001171549 |
| UniProt accession no. | P42226 |
| shipped in | wet ice |
| target post-translational modification | phosphorylation (pTyr641) |
| Gene Information | human ... STAT6(6778) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
¥ 1048.84
-
¥ 827.30
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 907.59
-
¥ 1152.81
-
¥ 540.59
-
¥ 2321.98
-
¥ 915.42
-
¥ 66743.99
-
¥ 44224.19
-
¥ 46052.83
-
¥ 65710.50
-
询价
-
¥ 402833.12
微信小程序
7X24小时在线咨询