Prostaglandin E₂,1MG,538904-1MGCN,Sigma

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订货号 : 0BV4675
品牌型号 : Sigma 538904-1MGCN
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

Involved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC50 = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.


Biochem/physiol Actions

Cell permeable: no
Primary Target
Involved in vasodilator actions of kinins such as bradykinin
Product does not compete with ATP.
Reversible: no
Target IC50: 25-50 µM inhibiting MAP kinase in rat mesangial cells


Other Notes

Li, X., et al. 1995. Am. J. Physiol.269, C986.
Kessler, W., et al. 1992. Exp. Brain Res.91, 467.


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Harmful (C)


技术参数 Specifications
Quality Level100
descriptionMerck USA index - 14, 7877
assay>98% (HPLC)
formsolid
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze
color white to light yellow
solubilityacetone: soluble,ethanol: soluble,ethyl acetate: soluble,methanol: soluble
shipped inwet ice
storage temp.−20°C
SMILES stringOC1C(C(C(=O)C1)C\C=C\CCCC(=O)O)\C=C\C(O)CCCCC
InChI1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4+,13-12+
InChI keyXEYBRNLFEZDVAW-RTYMFESYSA-N
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