- 商品介绍
- 规格参数
- 包装参数
General description
Involved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC50 = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Involved in vasodilator actions of kinins such as bradykinin
Product does not compete with ATP.
Reversible: no
Target IC50: 25-50 µM inhibiting MAP kinase in rat mesangial cells
Other Notes
Li, X., et al. 1995. Am. J. Physiol.269, C986.
Kessler, W., et al. 1992. Exp. Brain Res.91, 467.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
| Quality Level | 100 |
| description | Merck USA index - 14, 7877 |
| assay | >98% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze |
| color | white to light yellow |
| solubility | acetone: soluble,ethanol: soluble,ethyl acetate: soluble,methanol: soluble |
| shipped in | wet ice |
| storage temp. | −20°C |
| SMILES string | OC1C(C(C(=O)C1)C\C=C\CCCC(=O)O)\C=C\C(O)CCCCC |
| InChI | 1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4+,13-12+ |
| InChI key | XEYBRNLFEZDVAW-RTYMFESYSA-N |
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