Anti-IL-34 Antibody，100UG，ABF294，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages.
~47 kDa observed. Despite its predicted molecular weight of 27 kDa, IL-34 will often run at higher molecular weight in SDS-PAGE.

Immunogen

KLH-conjugated synthetic peptide corresponding to the N-terminus of human IL-34.
Epitope: N-terminus

Application

Anti-IL-34 Antibody detects level of IL-34 & has been published & validated for use in IL-34.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology

Physical form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in human brain tissue lysate with and without blocking peptide.

Western Blotting Analysis: 0.25 μg/mL of this antibody detected IL-34 in human brain tissue lysate with and without blocking peptide.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Segment	100
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
purified by	affinity chromatography
species reactivity	human
technique(s)	western blot: suitable
UniProt accession no.	Q6ZMJ4
shipped in	wet ice
target post-translational modification	unmodified
Gene Information	human ... IL34(146433)

长度(mm)
宽度(mm)
高度(mm)
重量(kg)