- 商品介绍
- 规格参数
- 包装参数
General description
130 kDa
Neuropilin-1 is a type 1 membrane protein with three distinct functions. First, it can mediate cell adhesion via a heterophilic molecular interaction. Second, in neuronal cells, neuropilin-1 binds the class 3 semaphorins, which are neuronal chemorepellents, and plays a role in the directional guidance of axons. It is expected to form complexes with the plexinA subfamily members and mediate the semaphorin-elicited inhibitory signals into neurons. Third, in endothelial cells, neuropilin-1 binds a potent endothelial cell mitogen, vascular endothelial growth factor (VEGF)165, and regulates vessel formation.
Immunogen
Epitope: Unknown
This antibody is generated from rabbits immunized with a His-tagged partial recombinant rat Neuropilin-1.
Application
Research Category
Neuroscience
Research Sub Category
Growth Cones & Axon Guidance
This Anti-Neuropilin-1 Antibody is validated for use in WB, IH, IP, IF for the detection of Neuropilin-1.
Biochem/physiol Actions
This antibody recognizes Neuropilin-1.
Physical form
Rabbit serum in buffer containing 0.05% sodium azide.
Unpurified
Preparation Note
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Analysis Note
Control
PC12 cell lysate
Evaluated by Western Blot in PC12 cell lysate.
Western Blot Analysis: : 1:1,000 dilution of this antibody detected Neuropilin 1 on 10 µg of PC12 cell lysate.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | serum |
| antibody product type | primary antibodies |
| clone | polyclonal |
| species reactivity | rat, mouse |
| species reactivity (predicted by homology) | human (94%) |
| technique(s) | immunofluorescence: suitable,immunohistochemistry: suitable,immunoprecipitation (IP): suitable,western blot: suitable |
| isotype | IgG |
| NCBI accession no. | NP_659566.1 |
| UniProt accession no. | Q9QWJ9 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... NRP1(8829) |
| 长度(mm) | |
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| 重量(kg) |
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¥ 2290.21
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¥ 3109.49
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¥ 238.17
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¥ 3372.68
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔¥ 1938.54
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¥ 15214.65
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¥ 8982.64
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¥ 2882.02
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