- 商品介绍
- 规格参数
- 包装参数
General description
Prohibitin is an inhibitor of DNA synthesis that is widely expressed across various tissues. Prohibitin influences proliferation, and may also have a role in regulating mitochondrial respiration activity and in aging. Expression levels of prohibitin in fibroblasts have been found to decrease heterogeneously as cellular aging occurs.
~30 kDa observed
Immunogen
KLH-conjugated linear peptide corresponding to human Prohibitin-1 (PHB1).
Application
Anti-Prohibitin-1 (PHB1), clone 1G5C1 | MABC965 is an antibody against Prohibitin-1 for use in Western Blotting, Immunohistochemistry.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Western Blotting Analysis: 1.0 µg/mL from a representative lot detected Prohibitin-1 (PHB1) in 10 µg of NIH/3T3 and HeLa cell lysate.
Immunohistochemistry Analysis: A representative lot detected Prohibitin-1 (PHB1) in rat liver tissue (Kakehashi, A., et al. (2011). Toxicological Sciences. 119(1):61-72).
Physical form
Format: Purified
Protein G Purified
Purified rat monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Evaluated by Western Blotting in rat liver tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Prohibitin-1 (PHB1) in 10 µg of rat liver tissue lysate.
Other Notes
Concentration: Please refer to lot specific datasheet.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rat |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified antibody |
| antibody product type | primary antibodies |
| clone | 1G5C1, monoclonal |
| species reactivity | human, mouse, rat |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| isotype | IgG2bκ |
| NCBI accession no. | NP_001268425 |
| UniProt accession no. | P35232 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... PHB(5245) |
| 长度(mm) | |
| 宽度(mm) | |
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