RAC2, His tagged human,50UG,SRP5122-50UG,Sigma

销售价: ¥ 2612.12 / 件
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订货号 0BV1713
品牌型号 Sigma SRP5122-50UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

RAC2 is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins and is involved in a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization and the activation of protein kinases. Knockdown of the gene for both RAC1 and RAC2 completely blocks B-cell development indicating that both GTPases are required to transduce B-cell receptor (BCR) signals leading to proliferation, survival, and the upregulation of BAFF receptor. Furthermore, RAC2 is required for the transfer of electrons from NADPH to cytochrome b-associated FAD, then to cytochrome b heme, and finally to oxygen.


Physical form

Supplied in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.


Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles


技术参数 Specifications
recombinantexpressed in E. coli
assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
mol wt ~22 kDa
NCBI accession no.NM_002872
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... RAC2(5880)
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