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- 规格参数
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Biochem/physiol Actions
VPC-13566 is Binding Function 3 (BF3)-specific inhibitor of the androgen receptor.
VPC-13566 is Binding Function 3 (BF3)-specific inhibitor of the androgen receptor. VPC-13566 potently inhibits AR transcriptional activity by displacement of the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines including an enzalutamide-resistant cell line and inhibits the growth of AR-dependent prostate cancer xenograft in mice.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | CC1=CC=CC2=C1NC=C2C3=NC4=CC=CC=C4C=C3 |
| InChI key | FPKBNOVQNMJTEJ-UHFFFAOYSA-N |
| 长度(mm) | |
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| 重量(kg) |
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