- 商品介绍
- 规格参数
- 包装参数
General description
This ELISA antibody pair detects mouse TNFSF4/OX40.
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Tumor necrosis factor (TNF) superfamily member 4 (Tnfsf4) signals specifically through the OX40 receptor, which is expressed primarily on CD4+T cells but also on certain activated CD8+T cells. Tnfsf4 acts as a costimulatory signal, which is essential for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival and increases expression of regulated on activation, normal T cell expressed and secreted (RANTES) or chemokine ligand 5 (CCL5), interleukins-2 and -3 and interferon γ (IFNg). Tnfsf4 signaling plays an important role in immuno-regulatory communication and immune-tolerance. Polymorphisms in the TNFSF4 gene leads to the development of autoimmune thyroid diseases (AITDs), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and systemic sclerosis (SSc).
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
| species reactivity | mouse |
| packaging | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable |
| input | sample type serum sample type plasma sample type cell culture supernatant(s) |
| assay range | inter-assay cv: <10% intra-assay cv: <12% sensitivity: 30 pg/mL |
| detection method | colorimetric |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | mouse ... Tnfsf4(22164) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
¥ 1665.68
-
询价
-
询价
-
询价
-
询价
-
¥ 1260.99
-
询价
-
询价
-
¥ 95.27
-
询价
-
询价
-
询价
-
¥ 6085.86
-
询价
-
¥ 1029.59
-
¥ 1066.63
-
¥ 502.32
-
¥ 520.54
-
¥ 2321.98
微信小程序
7X24小时在线咨询