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产品介绍
Product Description
Biochem/physiol Actions
AMPA-R potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons
HBT1 is an AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor] potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate dependent manner.
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| web metadata keyword.default | 2-(((5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetyl)amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide,AMPA-R potentiator 489408-02-8,AMPA-R potentiator Sigma-Aldrich,AMPA-R potentiator for neuroscience research,AMPA-R potentiator for primary neuron applications,BDNF production enhancer 489408-02-8,N-[3-(Aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-5-methyl-3-(trifluoromethyl) chemical,Sigma-Aldrich AMPA-R potentiator,brain-derived neurotrophic factor BDNF inducer 489408-02-8,high purity AMPA-R potentiator for lab use,neuroactive small molecules for research order,neuroscience research chemicals 489408-02-8,neurotrophic factor inducer small molecule |
| storage temp. | 2-8°C |
| SMILES string | O=C(N)C1=C(NC(CN2C(C)=CC(C(F)(F)F)=N2)=O)SC3=C1CCCC3 |
| InChI | 1S/C16H17F3N4O2S/c1-8-6-11(16(17,18)19)22-23(8)7-12(24)21-15-13(14(20)25)9-4-2-3-5-10(9)26-15/h6H,2-5,7H2,1H3,(H2,20,25)(H,21,24) |
| InChI key | PHLXSNIEQIKENK-UHFFFAOYSA-N |
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