- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
AGF347 is a potent inhibitor of serine hydroxymethyltransferase 2 (SHMT2) that inhibits mitochondrial C1 metabolism. It also inhibits cytosolic C1 targets such as SHMT1, GARFTase, and AICARFTase. AGF347 inhibits de novo purine biosynthesis. AGF347 exhibits potent broad spectrum in vitro and in vivo antitumor efficacy.
potent inhibitor of serine hydroxymethyltransferase 2 (SHMT2)
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/L, clear |
| storage temp. | 2-8°C |
| SMILES string | O=C(CC[C@H](NC(C1=CC=C(C=C1F)CCCCN2C=CC(N=C(N3)N)=C2C3=O)=O)C(O)=O)O |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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