Anti-FGFR3 antibody produced in rabbit，100UG，SAB4500888-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Anti-FGFR3 Antibody detects endogenous levels of total FGFR3 protein.

FGFR3 (fibroblast growth factor receptor 3) belongs to the fibroblast growth factor receptor (Fgfr) family of proteins. It has 19 exons, an extracellular ligand binding domain, a transmembrane domain and an intracellular tyrosine kinase domain. It is located on human chromosome 4p16.3.

Immunogen

The antiserum was produced against synthesized peptide derived from human FGFR3.

Immunogen Range: 131-180

Application

Anti-FGFR3 antibody has been used in immunohistochemistry.

Biochem/physiol Actions

Germline mutations in FGFR3 (fibroblast growth factor receptor 3) results in autosomal dominant skeletal dysplasias like achondroplasia (ACH), thanatophoric dysplasia (TD) and hypochrondroplasia (HCH). The gene also controls cellular activity.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Segment	100
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
mol wt	antigen 87 kDa
species reactivity	rat, mouse, human
concentration	~1 mg/mL
technique(s)	ELISA: 1:10000,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:1000
NCBI accession no.	P22607
UniProt accession no.	P22607
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... FGFR3(2261)

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