- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Cell permeable, potent, and selective allosteric inhibitor of phosphatase PPM1F that inhibits tissue invasion by PPM1F-overexpressing human cancer cells
LockdownPro, an esterified lockdown analog with better cell permeability, is a cell permeable, potent, and selective allosteric inhibitor of phosphatase PPM1F. LockdownPro potently inhibits tissue invasion by PPM1F-overexpressing human cancer cells. It does not inhibit PPM1F in vitro.
| Quality Segment | 100 |
| assay | ≥97% (HPLC) |
| form | (oil or liquid) |
| color | colorless to yellow |
| storage temp. | 2-8°C |
| SMILES string | CC(C1=CC=C(C=C1)OC2=CC(C(OCC)=O)=C(C(OCC)=O)C=C2)(C3=CC=C(OC4=CC(C(OCC)=O)=C(C(OCC)=O)C=C4)C=C3)C |
| InChI | 1S/C39H40O10/c1-7-44-35(40)31-21-19-29(23-33(31)37(42)46-9-3)48-27-15-11-25(12-16-27)39(5,6)26-13-17-28(18-14-26)49-30-20-22-32(36(41)45-8-2)34(24-30)38(43)47-10-4/h11-24H,7-10H2,1-6H3 |
| InChI key | ROEOSYBNNXMANC-UHFFFAOYSA-N |
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¥ 1125.70
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¥ 1349.07
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