Anti-IRF4 Antibody, clone 2U3G10, Rabbit Monoclonal,100UL,SAB5703003-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BU5859
品牌型号 Sigma SAB5703003-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IRF4 (Q15306).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone2U3G10, monoclonal
formliquid
mol wt 52 kDa
species reactivityhuman
concentration0.47 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceMNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCA
UniProt accession no.Q15306
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... IRF4(3662)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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