- 商品介绍
- 规格参数
- 包装参数
General description
A cell-permeable benzothiazolyl-acetamide compound that inhibits the cellular Wnt processing and secretion via selective blockage of MBOAT (membrane-bound O-acyltranferase) family member Porcn- (Porcupine) mediated Wnt palmitoylation. IWP-2 does not affect Wnt/β-catenin signaling pathway in general and, unlike IWR-1-endo (Cat. No. 681669), displays no effect against Wnt-stimulated cellular responses.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
Porcn
Reversible: yes
Packaging
Packaged under inert gas
Physical form
A 10 mM (5 mg/1.07 ml) sterile-filtered solution of Wnt Antagonist II, IWP-2 (Cat. No. 681671) in DMSO.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C. Warming to 60°C may be required upon initial thaw.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| Quality Segment | 100 |
| assay | ≥99% (HPLC) |
| form | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,avoid repeated freeze/thaw cycles,desiccated (hygroscopic),protect from light |
| storage temp. | −70°C |
| SMILES string | [s]1c2c(nc1NC(=O)CSc3[n]([c](c5c(n3)CCS5)=O)c4ccccc4)ccc(c2)C |
| InChI | 1S/C22H18N4O2S3/c1-13-7-8-15-17(11-13)31-21(23-15)25-18(27)12-30-22-24-16-9-10-29-19(16)20(28)26(22)14-5-3-2-4-6-14/h2-8,11H,9-10,12H2,1H3,(H,23,25,27) |
| InChI key | WRKPZSMRWPJJDH-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
¥ 916.08
-
¥ 521.16
-
¥ 807.83
-
¥ 1243.80
-
询价
-
询价
-
询价
-
询价
-
¥ 2290.18
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 633.78
-
¥ 852.85
-
¥ 540.59
-
¥ 2321.98
-
询价
微信小程序
7X24小时在线咨询