- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Alosetron is a potent and highly selective antagonist of serotonin 5-HT3 receptors, nonselective cation channels found predominantly in the enteric nervous system of the gastrointestinal tract. These receptors are involved in the regulation of visceral pain, colonic transit and GI secretions that can contribute to the pathophysiology of irritable bowel syndrome (IBS). Alosetron is used clinically for treatment of women with severe diarrhea-predominant IBS.
Alosetron is a potent and highly selective antagonist.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | H2O: ≥5 mg/mL at warmed |
| storage temp. | 2-8°C |
| SMILES string | CN1C2=C(C=CC=C2)C3=C1CCN(CC4=C(C)N=CN4)C3=O.Cl |
| InChI | 1S/C17H18N4O.ClH/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2;/h3-6,10H,7-9H2,1-2H3,(H,18,19);1H |
| InChI key | FNYQZOVOVDSGJH-UHFFFAOYSA-N |
| Gene Information | human ... HTR3A(3359) |
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¥ 2814.26
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¥ 1563.36
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¥ 6894.69
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¥ 1653.62
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¥ 14407.09
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¥ 2573.97
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¥ 3031.24
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¥ 2452.91
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¥ 954.17
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¥ 4614.63
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