2,3-二甲氧基-5-甲基-对苯醌,5G,D9150-5G,Sigma

销售价: ¥ 2644.81 / 件
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订货号 0BU3756
品牌型号 Sigma D9150-5G
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0 or DMM) is present in all the cells including neural cells.


Application

2,3-Dimethoxy-5-methyl-p-benzoquinone has been used:

  • as a tau protein fibrillization inducer to determine the regions of tau involved in the formation of paired helical filaments (PHFs)
  • as a component in buffer B for cytochrome oxidation assay with subsaturating light
  • in the RPMI-1640 medium for 2,3-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanilide (XTT) assay to quantify antifungal activity


Coenzyme Q0 inhibits (via radical quenching) reactions of gamma-irradiation induced homolytic cleavage of O-glycoside bonds in polysaccharides. Coenzyme Q0 induces apoptosis and modulates the cell cycle in estrogen receptor negative breast cancer cells. It is toxic to other cells such as insulin producing cells.


Biochem/physiol Actions

2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0) interacts with tau protein and aids in the formation of filamentous structure.


技术参数 Specifications
Quality Segment200
formpowder
mp58-60 °C (lit.)
storage temp.2-8°C
SMILES stringCOC1=C(OC)C(=O)C(C)=CC1=O
InChI1S/C9H10O4/c1-5-4-6(10)8(12-2)9(13-3)7(5)11/h4H,1-3H3
InChI keyUIXPTCZPFCVOQF-UHFFFAOYSA-N
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