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General description
This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human beta glucuronidase (GUSB) (P08236).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| material | colorless |
| clone | 4U0E2, monoclonal |
| form | liquid |
| mol wt | 75 kDa |
| species reactivity | human |
| concentration | 1 mg/mL |
| technique(s) | western blot: 1:500 - 1:2000 |
| color | colorless |
| isotype | IgG |
| immunogen sequence | MARGSAVAWAALGPLLWGCALGLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFEEQWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVW |
| UniProt accession no. | P08236 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... GUSB(2990) |
| 长度(mm) | |
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| 重量(kg) |
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¥ 459.57
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¥ 916.08
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¥ 673.51
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¥ 852.85
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¥ 8072.66
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¥ 18741.69
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¥ 26846.31
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