- 商品介绍
- 规格参数
- 包装参数
General description
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Biochem/physiol Actions
This Stat3 antibody is generated from a mouse immunized with Stat3 recombinant protein.
Physical form
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| biological source | (Human) |
| conjugate | unconjugated |
| antibody form | purified antibody |
| antibody product type | primary antibodies |
| clone | monoclonal |
| form | liquid |
| mol wt | 28303Da |
| species reactivity | human |
| technique(s) | western blot: 1:2000 |
| isotype | IgG2a, kappa |
| NCBI accession no. | P42227, Q19S50,P52631 |
| storage temp. | -10 to -25°C |
| target post-translational modification | unmodified |
| Gene Information | human ... STAT3(6774) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |




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