- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Application
Penfluridol has been used as an antipsychotic agent:
- to study its antimetastatic effect on triple-negative breast cancer cells
- to study its effects on the growth of glioblastoma cell lines,
- to study its effects on the vascular endothelial growth factor (VEGF)-induced angiogenesis in human umbilical vein endothelial cells (HUVECs)
Biochem/physiol Actions
Penfluridol is studied in the treatment of schizophrenia, Tourette syndrome and acute psychosis. It also exhibits anticancer activity.
T-type Ca2+ channel blocker; antipsychotic
Features and Benefits
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
技术参数
Specifications
| assay | ≥97% (HPLC) |
| form | powder |
| color | white |
| solubility | DMSO: >20 mg/mL,H2O: insoluble |
| originator | Johnson & Johnson |
| storage temp. | 2-8°C |
| SMILES string | OC1(CCN(CCCC(c2ccc(F)cc2)c3ccc(F)cc3)CC1)c4ccc(Cl)c(c4)C(F)(F)F |
| InChI | 1S/C28H27ClF5NO/c29-26-12-7-21(18-25(26)28(32,33)34)27(36)13-16-35(17-14-27)15-1-2-24(19-3-8-22(30)9-4-19)20-5-10-23(31)11-6-20/h3-12,18,24,36H,1-2,13-17H2 |
| InChI key | MDLAAYDRRZXJIF-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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