MART-1 (26-35), Human,5MG,M6449-5MG,Sigma

销售价: ¥ 5836.51 / 件
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订货号 : 0BU1025
品牌型号 : Sigma M6449-5MG
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

Melanoma-associated antigen recognized by T cells-1 (MART-1), also known as Melan-A, is encoded by the gene mapped to human chromosome 9p24.1. The encoded protein is a hydrophobic transmembrane protein. MART-1 is mainly expressed in skin and retinae melanocytes.
The peptide represents amino acids 26-35 of MART-1 protein that is the melanoma antigen recognized by T cells. This peptide mimics the natural epitope that is presented by T cells in humans with reactivity to melanoma cells.


Biochem/physiol Actions

Melanoma-associated antigen recognized by T cells-1 (MART-1) is essential for the functioning of glycoprotein-100 (gp100). Overexpression of the gene has been observed in cutaneous melanoma (CM). In addition, deletion of Mart-1 gene leads to parotid metastatic melanoma.


Physical form

Lyophilized from 0.1% aqueous TFA


Other Notes

Lyophilized from 0.1% TFA in H2O


技术参数 Specifications
formlyophilized powder
Quality Segment200
color white
solubilitywater, double-distilled: soluble
storage temp.−20°C
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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