Exo2,5MG,E7159-5MG,Sigma

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订货号 0BT9916
品牌型号 Sigma E7159-5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

Exo2 acts as a chemical probe of intracellular transport.
Exo2 acts as a chemical probe of intracellular transport. Edxo2 has activities similar to Brefeldin A with membrane trafficking to the Golgi appartus, but appears more selective.
Exo2 is a bioactive small molecule that activates Golgi-endoplasmic reticulum (ER) fusion in mammals by distorting the Golgi apparatus. It prevents the release of secretory cargo from the ER. Exo2 do not modify the morphology of the trans-Golgi network (TGN). It also inhibits the anterograde movement of vesicular stomatitis virus G (VSV G) glycoprotein, from ER to Golgi.


技术参数 Specifications
assay≥98% (HPLC)
formpowder
color yellow
solubilityDMSO: >20 mg/mL
storage temp.2-8°C
SMILES stringCOc1cc(ccc1O)\C=N\Nc2ncnc3sc4CCCCc4c23
InChI1S/C18H18N4O2S/c1-24-14-8-11(6-7-13(14)23)9-21-22-17-16-12-4-2-3-5-15(12)25-18(16)20-10-19-17/h6-10,23H,2-5H2,1H3,(H,19,20,22)/b21-9+
InChI keyVFNUTEMVQGLDAG-ZVBGSRNCSA-N
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