- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
T-26c is a highly potent, selective and cell-permeable matrix metalloproteinases 13 (MMP-13) inhibitor.
T-26c is a highly potent, selective and cell-permeable matrix metalloproteinases 13 (MMP-13) inhibitor. T-26c inhibits the breakdown of collagen (87.4% inhibition at 0.1 μM) in IL-1b and oncostatin M stimulated cartilage. For full characterization details, please visit the T-26c probe summary on the Structural Genomics Consortium (SGC) website.
To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc
Features and Benefits
T-26c is a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 10 mg/mL, clear |
| web metadata keyword.default | 4-[[[1,4-Dihydro-2-[[[(3-methoxyphenyl)methyl]amino]carbonyl]-4-oxothieno[2,3-d]pyrimidin-5-yl]methoxy]methyl]-benzoic acid,869296-13-9 T-26c chemical probe,Sigma-Aldrich T-26c for research,T-26c 869296-13-9 for laboratory use,T-26c MMP-13 inhibitor,T-26c cell-permeable inhibitor,T-26c chemical probe from Structural Genomics Consortium,T-26c for metalloproteinase research,T-26c in vitro research chemical,T-26c inhibitor,T-26c lab-grade MMP-13 inhibitor,T-26c,high purity T-26c for biological studies,selective MMP-13 inhibitor T-26c |
| storage temp. | 2-8°C |
| SMILES string | OC(C(C=C1)=CC=C1COCC2=CSC3=C2C(NC(C(NCC4=CC=CC(OC)=C4)=O)=N3)=O)=O |
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