- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
Potent and selective CaM kinase kinase (CaMKK) inhibitor with selective affinity toward CAMKK1/2 over other kinases.
SGC-CAMKK2-1 (YL-36) is a potent and selective CaM kinase kinase (CaMKK) inhibitor (CAMKK2 IC50 = 30 nM) that inhibits C4-2 cellular AMPK phosphorylation (IC50 = 1.6 μM) with selective affinity toward CAMKK1/2 over other kinases (404-kinase panel kinome-wide Discoverx screen).
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | CC1=CC(C2=CN=C(OC=C3C4=CC(C5CCCC5)=C(C(O)=O)C=C4)C3=C2)=CC=C1 |
| InChI | 1S/C26H23NO3/c1-16-5-4-8-18(11-16)20-13-23-24(15-30-25(23)27-14-20)19-9-10-21(26(28)29)22(12-19)17-6-2-3-7-17/h4-5,8-15,17H,2-3,6-7H2,1H3,(H,28,29) |
| InChI key | TXIYVFVMXNFNRX-UHFFFAOYSA-N |
| 长度(mm) | |
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| 重量(kg) |
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