Anti-Human IgG (Fab specific)-Peroxidase antibody, Mouse monoclonal,1VIAL,SAB4200791-1VL,Sigma

销售价: ¥ 6152.62 / 件
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订货号 0BT9047
品牌型号 Sigma SAB4200791-1VL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Anti-Human IgG (Fab specific)-Peroxidase antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the GG-6 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from mouse immunized with purified human IgG (Fab fragment). IgGs are the most common Immunoglobulins isotype in blood, lymph fluid, cerebrospinal fluid and peritoneal fluid and a key players in the humoral immune response. IgGs include four subclasses (IgG1, IgG2, IgG3, and IgG4), they consist of a variable Fab fragment (which includes the antibody recognition site), and a conserved Fc fragment. The IgG subclasses differ in their physical and chemical properties, their distribution pattern is found to be age-dependent, and every subclass has a specific biological function.


Immunogen

Purified human IgG (Fab Fragment)


Application

Direct ELISA: a working dilution of 1:16,000-1:32,000 is recommended using 2.5 μg/mL human IgG for coating.


Biochem/physiol Actions

Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. Maternal IgG is the only antibody transported across the placenta to the fetus. Maternal IgG passively immunizes the infants. IgG deficiencies are often associated with various diseases.


Physical form

Supplied as a lyophilized powder.


Other Notes

In order to obtain best results in different techniques and preparations we recommend determining optimal working concentration by titration test.


技术参数 Specifications
biological sourcemouse
Quality Level200
conjugateperoxidase conjugate
antibody formpurified from hybridoma cell culture
antibody product typeprimary antibodies
cloneGG-6, monoclonal
formlyophilized powder
species reactivityhuman
concentration~2 mg/mL
technique(s)direct ELISA: 1:16,000-1:32,000 using 2.5 μg/ml human IgG for coating.
isotypeIgG1
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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