小鼠Tyro3 /酪氨酸蛋白激酶受体TYRO3 ELISA试剂盒,96WELLS,RAB0780-1KT,Sigma

销售价: ¥ 4860.53 / 件
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订货号 0BT8460
品牌型号 Sigma RAB0780-1KT
货期 询货期
最小订货量 1件
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  • 商品介绍
  • 规格参数
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产品介绍 Product Description

General description

The antibody pair provided in this kit recognizes mouse Tyro3.


Application

请参考Protocol了解详情。


Biochem/physiol Actions

Tyrosine-protein kinase receptor (TYRO3) is a transmembrane tyrosine kinase receptor. It plays a significant role in the brain development during embryogenesis. It plays an important role in apoptotic cell clearance. In hepatocellular carcinoma, it is associated with tumor growth, aggressiveness and liver dysfunction. Mutations in the TYRO3 gene intronic regions are linked with asthma. TYRO3 is also a suppressor of type 2 immunity. As part of the TAM (TYRO3, AXL and MER receptors) family, it is activated by PROS1 (protein S) and GAS6 (growth arrest-specific gene 6). Changes in the expression of TYRO3 are linked with the proliferation and survival of cancer cells. Absence of TYRO3 in mice results in neurological disorders.


技术参数 Specifications
species reactivitymouse
packagingkit of 96 wells (12 strips x 8 wells)
technique(s)ELISA: suitable
inputsample type cell culture supernatant(s)
sample type serum
sample type plasma
assay rangeinter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.4 ng/mL
standard curve range: 0.416-100 ng/mL
detection methodcolorimetric
shipped inwet ice
storage temp.−20°C
Gene Informationmouse ... Tyro3(22174)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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