- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Toloxatone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant.
Toloxatone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant. Toloxatone belongs to the aryloxazolidinones, a relatively new class of reversible monoamine oxidase A inhibitors (MAOI). Studies show that derivatives such as 3-aryloxazolidin-2-one (oxazolidinones), which are regularly used to treat gram positive infections, represent a new class of reversible as well as irreversible inhibitors for MAO-A and MAO-B enzymes that are able to inhibit protein synthesis and also used for neurodegenerative-type pathologies.
Preparation Note
Toloxatone is soluble in DMSO at a concentration that is greater than 10 mg/ml.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| storage condition | desiccated |
| solubility | DMSO: >10 mg/mL |
| storage temp. | 2-8°C |
| SMILES string | Cc1cccc(c1)N2CC(CO)OC2=O |
| InChI | 1S/C11H13NO3/c1-8-3-2-4-9(5-8)12-6-10(7-13)15-11(12)14/h2-5,10,13H,6-7H2,1H3 |
| InChI key | MXUNKHLAEDCYJL-UHFFFAOYSA-N |
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