Anti-NF-κB2 Antibody, clone 4K3V3, Rabbit Monoclonal，100UL，SAB5702194-100UL，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Immunogen

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 745-877 of human NF-κB2 (Q00653).

Application

WB, IHC

技术参数 Specifications

biological source	rabbit
Quality Segment	100
conjugate	unconjugated
material	colorless
clone	4K3V3, monoclonal
form	liquid
mol wt	120 kDa
species reactivity	rat, human
concentration	0.25 mg/mL
technique(s)	immunohistochemistry: 1:50 - 1:200,western blot: 1:500 - 1:2000
color	colorless
isotype	IgG
immunogen sequence	LLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQLLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGLEEGVRLLRGPETRDKLPSTAEVKEDSAYGSQSVEQEA
UniProt accession no.	Q00653
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... NFKB2(4791)

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