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- 规格参数
- 包装参数
General description
HOXD11 is a homeobox transcription factor that regulates morphogenesis. It is known to modulate metanephric kidney development in mouse embryos. Hoxd11 mutations have been linked to axial skeleton homeostasis and forelimb malformations.
Rabbit Anti-HOXD11 antibody recognizes human, bovine, mouse, and canine HOXD11.
Immunogen
Synthetic peptide directed towards the middle region of human HOXD11
Application
Rabbit Anti-HOXD11 antibody can be used for western blot applications at a concentration of 0.25μg/ml.
Biochem/physiol Actions
HOXD11 belongs to the homeobox family. This family play an important role in morphogenesis in all multicellular organisms. The mouse Hoxd11 plays a role in forelimb morphogenesis.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5′ end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: GFDQFYEAAPGPPFAGPQPPPPPAPPQPEGAADKGDPRTGAGGGGGSPCT
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 35 kDa |
| species reactivity | human |
| concentration | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| web metadata keyword.default | Anti-HOXD11 antibody for developmental biology applications,HOXD11 antibody for bovine and canine studies,Rabbit Anti-HOXD11 antibody 0.09% sodium azide,Rabbit Anti-HOXD11 antibody for western blot,Rabbit Anti-HOXD11 antibody recognition of human HOXD11,Rabbit Anti-HOXD11 antibody,Rabbit anti-HOXD11 antibody 0.25µg/ml,Sigma-Aldrich Rabbit Anti-HOXD11 antibody,anti-HOXD11 antibody applications in morphogenesis,anti-HOXD11 antibody for kidney development research,anti-HOXD11 polyclonal antibody for mouse studies,homeobox D11 antibody for axial skeleton research,purified Rabbit Anti-HOXD11 antibody 1x PBS,western blot grade Anti-HOXD11 antibody |
| NCBI accession no. | NP_067015 |
| UniProt accession no. | A6NIS4 |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... HOXD11(3237) |
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¥ 2814.26
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