CHR-6494 trifluoroacetate salt,5MG,SML0648-5MG,Sigma

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订货号 0BT4627
品牌型号 Sigma SML0648-5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation. CHR-6494 causes cell cycle arrest in G2/M and subsequent apoptosis. CHR-6494 causes an abnormal duplication of centrosomes and mitotic catastrophe in cancer cells.
CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor.


技术参数 Specifications
Quality Segment100
assay≥98% (HPLC)
formpowder
color white to beige
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.2-8°C
SMILES stringOC(=O)C(F)(F)F.CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1
InChI1S/C16H16N6.C2HF3O2/c1-2-7-17-15-5-6-16-18-10-14(22(16)21-15)11-3-4-13-12(8-11)9-19-20-13;3-2(4,5)1(6)7/h3-6,8-10H,2,7H2,1H3,(H,17,21)(H,19,20);(H,6,7)
InChI keyILWYDZNXJQESDI-UHFFFAOYSA-N
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