Anti-Phospho-PLC gamma 1 (PLCG1)-Y783 antibody produced in rabbit,100UL,SAB5701747-100UL,Sigma

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订货号 : 0BT2991
品牌型号 : Sigma SAB5701747-100UL
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.


Immunogen

A phospho specific peptide corresponding to residues surrounding Y783 of human PLC gamma 1 (PLCG1)


Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
antibody product typeprimary antibodies
clonepolyclonal
formliquid
species reactivitymouse, rat, human
concentration1.59 mg/mL
technique(s)western blot: 1:500-1:2000
UniProt accession no.P19174
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pTyr783)
Gene Informationhuman ... PLCG1(5335)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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