Monoclonal Anti-ELA3B, (C-terminal) antibody produced in mouse，100UG，SAB1403141-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. (provided by RefSeq)

Immunogen

ELA3B (AAH05216, 19 a.a. ~ 270 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
GPPSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSSWTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALLPVVDYEHCSRWNWWGSSVKKTMVCAGGDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRKPTVFTRVSAFIDWIEETIASH

Physical form

Solution in phosphate buffered saline, pH 7.4

技术参数 Specifications

biological source	mouse
Quality Segment	100
conjugate	unconjugated
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	2H6, monoclonal
form	buffered aqueous solution
mol wt	antigen ~53.83 kDa
species reactivity	human
technique(s)	capture ELISA: suitable,indirect ELISA: suitable
isotype	IgG1κ
NCBI accession no.	BC005216
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... ELA3B(23436)

长度(mm)
宽度(mm)
高度(mm)
重量(kg)