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General description
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic phosphorylated peptide around T204 of human BRD4 (NP_490597.1).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Application
WB
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| material | colorless |
| clone | 3V5R1, monoclonal |
| form | liquid |
| mol wt | 200 kDa |
| species reactivity | rat, human |
| concentration | 1.00 mg/mL |
| technique(s) | western blot: 1:500 - 1:1000 |
| color | colorless |
| isotype | IgG |
| immunogen sequence | ASTPP |
| UniProt accession no. | O60885 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... BRD4(23476) |
| 长度(mm) | |
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¥ 1596.77
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¥ 14407.09
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¥ 4404.38
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¥ 2268.97
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¥ 1749.15
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¥ 745.60
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¥ 1586.69
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¥ 26022.64
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¥ 17652.29
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