- 商品介绍
- 规格参数
- 包装参数
General description
Erdosteine is a derivative of thiol, and is used in the treatment of chronic obstructive bronchitis, including acute infective exacerbation of chronic bronchitis.It consists of two blocked sulfhydryl groups, which are released following first-pass metabolism.
Application
Erdosteine has been used as a mucolytic to study its protective effects on interleukin-1β-stimulated inflammation in rat chondrocytes in osteoarthritis models.
Biochem/physiol Actions
Erdosteine is a mucolytic drug with expectorant and antitussive effects. Erdosteine is quickly metabolized in vivo to free thiols which act as free radical scavengers. Erdosteine has also been shown to have antioxidant activity through the activation of Nrf2-dependent antioxidant genes and inhibition of pro-inflammatory cytokines.
Erdosteine is a mucolytic drug with expectorant and antitussive effects.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | S1CCC(C1=O)NC(=O)CSCC(=O)O |
| InChI | 1S/C8H11NO4S2/c10-6(3-14-4-7(11)12)9-5-1-2-15-8(5)13/h5H,1-4H2,(H,9,10)(H,11,12) |
| InChI key | QGFORSXNKQLDNO-UHFFFAOYSA-N |
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¥ 1573.49
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¥ 2307.00
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¥ 2869.87
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¥ 3896.11
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¥ 3796.67
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¥ 70526.15
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¥ 75435.65
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¥ 14985.93
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¥ 15537.49
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¥ 55311.07
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¥ 58184.19
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¥ 6431.00
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