- 商品介绍
- 规格参数
- 包装参数
Application
ENMD-1068 hydrochloride has been used as a protease-activated receptor 2 (PAR2) antagonist to determine the pathway responsible for paw edema induced by Crotalus durissus terrificus venom serine protease (Cdtsp 2).
Biochem/physiol Actions
ENMD-1068 hydrochloride exhibits anti-angiogenic and anti-inflammatory activities.
ENMD-1068 is an antagonist of protease-activated receptor 2 (PAR2).
ENMD-1068 is an antagonist of protease-activated receptor 2 (PAR2). The compound blocks TNFα production in synovial explants from patients with arthritis, and inhibits mast cell tryptase-induced recruitment of eosinophils into the pleural cavity of mice.
| Quality Segment | 100 |
| assay | ≥97% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | H2O: 25 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | N1(CCN(CC1)C(=O)CCCCCN)C(=O)CC(C)C |
| InChI | 1S/C15H29N3O2/c1-13(2)12-15(20)18-10-8-17(9-11-18)14(19)6-4-3-5-7-16/h13H,3-12,16H2,1-2H3 |
| InChI key | VRZYMMVEALDDBH-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 12156.68
-
¥ 1302.89
-
¥ 1451.54
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 3372.68
-
¥ 20380.83
-
¥ 2268.97
-
¥ 3335.66
-
¥ 2099.27
-
¥ 5804.96
-
询价
-
¥ 5990.26
微信小程序
7X24小时在线咨询