- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
VU0071063 is also known as [7-(4-(tert-butyl)benzyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione]. It serves as a major compound for examining β-cell physiology, KATP channel gating and a new chemical scaffold for evolving enhanced activators with medicinal chemistry.
VU0071063 is a potent activator of Kir6.2/SUR1 KATP channels (EC50 = 10.3 μM). VU0071063 reversibly inhibits glucose-stimulated calcium influx in mouse β-islet cells. The compound VU0071063 has no affect on Kir6.2/SUR2A channels.
VU0071063 is a specific activator of SUR1-containing KATP channels.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 10 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | CN(C1=C2N(CC3=CC=C(C(C)(C)C)C=C3)C=N1)C(N(C)C2=O)=O |
| InChI | 1S/C18H22N4O2/c1-18(2,3)13-8-6-12(7-9-13)10-22-11-19-15-14(22)16(23)21(5)17(24)20(15)4/h6-9,11H,10H2,1-5H3 |
| InChI key | ZFZAIHKQJBMYLO-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
¥ 1779.22
-
¥ 1866.29
-
¥ 1451.54
-
询价
-
询价
-
询价
-
¥ 3275.78
-
询价
-
询价
-
¥ 5725.45
-
¥ 2883.61
-
询价
-
¥ 20380.83
-
¥ 1564.00
-
¥ 1749.15
-
¥ 5061.38
-
询价
-
询价
-
¥ 44224.19
微信小程序
7X24小时在线咨询