- 商品介绍
- 规格参数
- 包装参数
General description
Doxepin is used to treat chronic idiopathic urticaria, chronic pain and anxiety. Doxepin exhibits antiserotonergic properties.
Biochem/physiol Actions
Tricyclic antidepressant that is a more potent inhibitor of norepinephrine uptake than of serotonin uptake; antagonist at H1 histamine, muscarinic cholinergic, and α-adrenoreceptors.
Features and Benefits
This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Other Notes
顺式和反式异构体混合物
| Quality Level | 200 |
| assay | ≥98% (GC) |
| form | powder |
| composition | Z-isomer, 15% ,E-isomer, ~85% |
| color | white to off-white |
| solubility | 1 M HCl: 50 mg/mL,H2O: soluble |
| originator | Boehringer Ingelheim |
| SMILES string | Cl[H].CN(C)CC\C=C1/c2ccccc2COc3ccccc13 |
| InChI | 1S/C19H21NO.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H/b17-11+; |
| InChI key | MHNSPTUQQIYJOT-SJDTYFKWSA-N |
| Gene Information | human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133), HRH1(3269), HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363) |
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¥ 2290.21
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¥ 1563.36
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¥ 1302.89
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¥ 2883.61
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¥ 3812.28
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¥ 2151.46
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¥ 2268.97
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¥ 5804.96
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¥ 64659.66
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