Monoclonal Anti-GFRA1 antibody produced in mouse,100UG,SAB1409108-100UG,Sigma

销售价: ¥ 4046.38 / 件
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订货号 0BT0837
品牌型号 Sigma SAB1409108-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. (provided by RefSeq)


Immunogen

GFRA1 (NP_005255, 32 a.a. ~ 119 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
ASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDS


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone4G3, monoclonal
formbuffered aqueous solution
mol wtantigen 35.31 kDa
species reactivityhuman
technique(s)immunofluorescence: suitable,indirect ELISA: suitable
isotypeIgG2bκ
NCBI accession no.NM_005264
UniProt accession no.P56159
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... GFRA1(2674)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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